Publications

2023

Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors

Pere Llinàs‐Arias, Miquel Ensenyat‐Méndez, Sandra Íñiguez‐Muñoz, Javier I. J. Orozco, Betsy Valdez, Matthew P Salomon, Chikako Matsuba, Maria Solivellas-Pieras, Andrés F Bedoya-López, Borja Sesé, Anja Mezger, Mattias Ormestad, Fernando Unzueta, Siri H Strand, Alexander D Boiko, E Shelley Hwang, Javier Cortés, Maggie L DiNome, Manel Esteller, Mathieu Lupien, Diego M Marzese 

BMC Molecular Cancer. 2023. PMID: 38017545 PMCID: PMC10683115 DOI: 10.1186/s12943-023-01906-8

3‐D chromatin conformation, accessibility, and gene expression profiling of triple‐negative breast cancer.

Pere Llinàs‐Arias, Miquel Ensenyat‐Méndez, Javier I. J. Orozco, Sandra Íñiguez‐Muñoz, Betsy Valdez, Chuan Wang, Anja Mezger, Eunkyoung Choi, Yan Zhou Tran, Liqun Yao, Franziska Bonath, Remi‐André Olsen, Mattias Ormestad, Manel Esteller, Mathieu Lupien and Diego M. Marzese

BMC Genomic Data. 2023;24:61.

Epigenetic Profiles of Triple-Negative Breast Cancer of African American and White Females. 

Ensenyat-Mendez M, Solivellas-Pieras M, Llinàs-Arias P, Íñiguez-Muñoz S, Baker JL, Marzese DM, DiNome ML.

JAMA Netw Open. 2023 Oct 2;6(10):e2335821. doi: 10.1001/jamanetworkopen.2023.35821. PMID: 37796506

Construction and validation of a gene expression classifier to predict immunotherapy response in primary triple-negative breast cancer.

Ensenyat-Mendez M, Orozco JIJ, Llinàs-Arias P, Íñiguez-Muñoz S, Baker JL, Salomon MP, Martí M, DiNome ML, Cortés J, Marzese DM.

Commun Med (Lond). 2023 Jul 10;3(1):93. doi: 10.1038/s43856-023-00311-y. PMID: 37430006

Multiplatform Analysis of Intratumoral PTEN Heterogeneity in Melanoma.

Chagani S, De Macedo MP, Carapeto F, Wang F, Marzese DM, Wani K, Haydu LE, Peng W, Ong GT, Warren SE, Beechem JM, Hoon DSB, Mills GB, Tetzlaff MT, Lazar AJ, Kwong LN, Davies MA.

J Invest Dermatol. 2023 Mar 4:S0022-202X(23)00164-1. doi: 10.1016/j.jid.2023.01.034. PMID: 36871660

2021

Epigenetic Regulation of Immunotherapy Response in Triple-Negative Breast Cancer.

Llinàs-Arias P, Íñiguez-Muñoz S, McCann K, Voorwerk L, Orozco JIJ, Ensenyat-Mendez M, Sesé B, DiNome ML, Marzese DM.

Cancers (Basel). 2021 Aug 17;13(16):4139. doi: 10.3390/cancers13164139.

PMID: 34439290

iGlioSub: an integrative transcriptomic and epigenomic classifier for glioblastoma molecular subtypes.

Ensenyat-Mendez M, Íñiguez-Muñoz S, Sesé B, Marzese DM.

BioData Min. 2021 Aug 23;14(1):42. doi: 10.1186/s13040-021-00273-8.

PMID: 34425860

Chromatin insulation dynamics in glioblastoma: challenges and future perspectives of precision oncology.

Sesé B, Ensenyat-Mendez M, Iñiguez S, Llinàs-Arias P, Marzese DM.

Clin Epigenetics. 2021 Jul 31;13(1):150. doi: 10.1186/s13148-021-01139-w.

PMID: 34332627 

Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens.

Orozco JIJ, Chang SC, Matsuba C, Ensenyat-Mendez M, Grunkemeier GL, Marzese DM, Grumley JG.

Ann Surg Oncol. 2021 Jul 9. doi: 10.1245/s10434-021-10457-5. Online ahead of print.

PMID: 34244898

Current Triple-Negative Breast Cancer Subtypes: Dissecting the Most Aggressive Form of Breast Cancer.

Ensenyat-Mendez M, Llinàs-Arias P, Orozco JIJ, Íñiguez-Muñoz S, Salomon MP, Sesé B, DiNome ML, Marzese DM.

Front Oncol. 2021 Jun 16;11:681476. doi: 10.3389/fonc.2021.681476. eCollection 2021.

PMID: 34221999

A Systems Approach to Brain Tumor Treatment.

Park JH, de Lomana ALG, Marzese DM, Juarez T, Feroze A, Hothi P, Cobbs C, Patel AP, Kesari S, Huang S, Baliga NS.

Cancers (Basel). 2021 Jun 24;13(13):3152. doi: 10.3390/cancers13133152.

PMID: 34202449

Familial Psychosis Associated With a Missense Mutation at MACF1 Gene Combined With the Rare Duplications DUP3p26.3 and DUP16q23.3, Affecting the CNTN6 and CDH13 Genes.

Pol-Fuster J, Cañellas F, Ruiz-Guerra L, Medina-Dols A, Bisbal-Carrió B, Asensio V, Ortega-Vila B, Marzese D, Vidal C, Santos C, Lladó J, Olmos G, Heine-Suñer D, Strauch K, Flaquer A, Vives-Bauzà C.

Front Genet. 2021 Apr 7;12:622886. doi: 10.3389/fgene.2021.622886. eCollection 2021.

PMID: 33897758

A Microcosm of Disparities in Breast Cancer: Comparison Between a Private Hospital and a Safety-Net County Hospital Within Los Angeles County.

McClintock NC, Ayabe RI, Salas Parra RD, Kaji AH, Orozco JIJ, Marzese DM, Samuels E, Stern SL, Dauphine C, Ozao-Choy JJ.

Am Surg. 2021 Feb 25:3134821998668. doi: 10.1177/0003134821998668. Online ahead of print.

PMID: 33629873